- Company Name:
- Membership:Free Member
- Registration Date:2016. 05.10
- Country/Region:China
- City:Shanghai
- Contact:Shelley Qian
- Related Keywords:Florfenicol, Antibiotics Antiviral Preparations, veterinary medicine
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Shanghai Tongren Pharmaceutical Co., Ltd.
[China]
Property a colorless or light golden sterile non-aqueous solution for injection
Pharmacological action
Pharmacodynamics
Florfenicol injection is a broad-spectrum bacteriophage, whose anti-bacteria mechanism is similar to that of Thiamphenical, which functions mainly by restraining the combination of bacteria 70S ribosome with 50S idene, and delay the function of peptidylamide transferase and to eventually control the expansion of peptide chain, and interfere with bacterial protein synthesis, thus present inhibitory effect in gram-negative and gram-positive
Pharmacokinetics
One hour after injecting the muscle, it can reach the treatment concentration in the blood. After 1 to 3 hours, it can reach the peak medicine concentration. The effective concentration of NiKang remain for over 48-72 hours. It can penetrate through the blood brain barrier. Its biology utilize ratio was 88.8%. It was mainly metabolized through liver and kidney, only a small amount was excreted from feces
Therapeutic indications
Florfenicol injection is a broad-spectrum synthetic antibiotic active against most Gram-positive and Gram-negative bacteria. It can be used to control bacterial disease of swine, chicken and fishies caused by susceptible bacteria. It is recommended for use in swine suffering from the following bacterial infection: contagious pleuropneumoniae, asthma, atrophic rhinitis, swine erysipelas, swine pasleurellosis, yellow scour of newborn piglet, while scour, Escherichia coli, agalactosis syndrome and other bacterial diseases. It can also be recommended to treat chickens respiratory infection due to pasteurella multocida.
Administration and Dosage
For swine and chicken: 0.67ml/10kg, of body weight by the intramuscular injection twice at 48 hours intervals
For fishes: 0.5-1.0mg/kg of body weight, once a day.
Side-effects not sure
precautions
1.Not recommended to use in lactating and pregnant animals
2.The volume administered per injection site should not exceed 10ml
3.Use a dry sterile syringe and needle
Withdrawal period Swine 14days, chicken 28 days, fish 375 degree days
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